Read the passage and answer the question. Stress is a widespread occurrence that impacts individuals of various ages and backgrounds. It is the body's normal reaction to challenging or threatening circumstances, setting off a chain of physiological processes meant to assist people in coping. Hormones like cortisol and adrenaline are released during these reactions, preparing the body for a 'fight or flight' response. Stress can be good in the short term since it helps with performance and focus, but long-term stress can be harmful to health. Extended exposure to stress hormones can cause depression, anxiety, reduced immunity and cardiovascular diseases. Chronic stress can also have a detrimental effect on digestion, sleep quality and general well-being. Managing stress effectively is crucial for maintaining good health. Common strategies include regular physical activity, meditation, deep-breathing exercises, a healthy work-life balance and social support from friends and family. Which of the following is NOT mentioned as a health issue caused by chronic stress?

1. Cardiovascular disease
2. Diabetes
3. Depression
4. Anxiety